Sploder (Resident Evil Revelations 2)

Under random circumstances, an Afflicted can undergo another mutation upon its death. This mutation causes pustules to erupt within its torso, causing the entire upper half of its body to become a sack of bile. The creature will then rise up again and pursue you.

They are encountered during Claire and Moira's scenarios. When they get within a certain proximity to you, or if they sustain a certain amount of damage, their bodies will explode causing major damage. Their demise will also spray the immediate area with their bile, causing your vision to become compromised if you are caught in the blast radius.